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Nasal Probiotic Efficacy in Allergic Rhinitis

Nasal Probiotic Efficacy in Perennial Allergic Rhinitis Symptom Control and Recurrence

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150716023235N19
Enrollment
64
Registered
2023-12-09
Start date
2023-11-22
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Allergic Rhinitis. Allergic rhinitis due to pollen

Interventions

Intervention 1: Intervention group: (Probiotic group) - In the first month, participants will use Mometasone nasal spray with probiotic nasal spray twice daily. In the second and third months, they wi

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
8 Years to 50 Years

Inclusion criteria

Inclusion criteria: All patients with chronic allergic rhinitis who have clinical symptoms consistent with allergic rhinitis and a positive skin test with aeroallergens Age above 8 years and less than 50 years Patient satisfaction

Exclusion criteria

Exclusion criteria: Taking antibiotics while taking probiotics Consumption of compounds containing probiotics other than the medicine prescribed in the study Suspected drug allergy symptoms The patient's non-cooperation in regular drug use and tests Pregnancy Taking immunosuppressive drugs Malnutrition Having a history of autoimmune disease or cystic fibrosis Active sinus infection, sinus pain, increased thick nasal secretions

Design outcomes

Primary

MeasureTime frame
Nasal smear eosinophils. Timepoint: Before intervention, after 1 and 3 months of intervention. Method of measurement: Microscopical observation.;Clinical symptoms. Timepoint: Before intervention, after 1 and 3 months of intervention. Method of measurement: SNOT22 Questionnaire.;Quality of Life. Timepoint: Before intervention, after 1 and 3 months of intervention. Method of measurement: miniRQLQ Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRana Tafrishi

Mashhad University of Medical Sciences

ranatafrishi96@gmail.com+98 51 3801 2298

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026