Effects of Pantoprazole in patients with caustic injuries of esophagus and stomach

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015071523215N1

Enrollment

Registered

2015-07-26

Start date

2015-08-06

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: caustic injury of esophagus. Condition 2: caustic injury of stomach. Corrosion of oesophagus Corrosion of other parts of alimentary tract

Interventions

pantoprazole with initial loading dose of 80 mg and maintenance dose of 8 mg per hour as continuous infusion in 36 hours.

Treatment - Drugs

pantoprazole with initial loading dose of 80 mg and maintenance dose of 8 mg per hour as continuous infusion in 36 hours

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: referring to the hospital with grade II caustic injuries of esophagus and/or stomach. Exclusion criteriona: presence of signs and symptoms of perforation and peritonitis.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Grade of esophageal burns by Zargar's classification for caustic injuries. Timepoint: 36 hours. Method of measurement: Endoscopy.;Grade of gastric burns by Zargar's classification for caustic injuries. Timepoint: 36 hours. Method of measurement: Endoscopy.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Hassan Peyvandi

Loghman Hakim hospital / Shahid Beheshti University of Medical Sciences

hassan.peyvandi@gmail.com+98 21 5102 5000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026