Cutaneous Leishmaniasis. Cutaneous leishmaniasis
Conditions
Interventions
Intervention group: Fibroblast Transplantation on number of 5 patients suffered from Cutaneous leishmaniasis to regenerate scar lesions after three subsequent fibroblast injections (2o mil/ turn) with
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 65 Years
Inclusion criteria
Inclusion criteria: Ages 15-65 Scar lesions caused by Cutaneous leishmaniasis grade 3 to 7; The willingness to provide informed consent for participation in the trial and the ability to communicate with the investigator during follow ups.
Exclusion criteria
Exclusion criteria: Use of Retinoids in the last 6 months Pregnancy Laser therapy in the last 6 months Cancer or any chronic systemic disease Chemical therapy Mesotherapy Active infection to Leishmaniasis in the scar Oragan or cell transplantation Autoimmune disease Breast feeding Dermal Filler in the last 6 months Plastic surgery at the site of Cutaneous leishmaniasis lesion Use of Corticosteroids Excessive exposure to sun. Subjects who are enrolled in any other clinical trial using systemic medication; or any other treatment that might interfere with this study Subjects with evidence of infection on area to be treated or elsewhere on body.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dermal thickness. Timepoint: Before intervention, 2, 6 and 12 months after the third transplantation of Fibroblasts. Method of measurement: Sonography.;Elasticity. Timepoint: Before intervention, 2, 6 and 12 months after the third transplantation of Fibroblasts. Method of measurement: Cotometer.;Wound Diameter. Timepoint: Before intervention, 2, 6 and 12 months after the third transplantation of Fibroblasts. Method of measurement: visioFace. | — |
Secondary
| Measure | Time frame |
|---|---|
| Patients Satisfaction. Timepoint: Before intervention, 2, 6 and 12 months after the third transplantation of Fibroblasts. Method of measurement: Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFaezeh Faghihi
Iran University of Medical Sciences
Outcome results
None listed