effect of Melissa officinalis on the anxiety

Investigating the effect of Melissa officinalis extract on the anxiety of patients undergoing orthopedic surgeries

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150713023190N4

Enrollment

Registered

2018-08-05

Start date

2018-08-06

Completion date

Unknown

Last updated

2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Surgery anxiety.

Interventions

Intervention 1: Intervention group: Patients in the intervention group receive 500 mg capsules containing Melissa officinalis extract at 4 and 10 pm before the surgery. Intervention 2: Control group:

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Candidate for orthopedic surgery Not being emergency patient Consent for participate in study Between 18-60 years old

Exclusion criteria

Exclusion criteria: Previous history of orthopedic surgery Use of Melissa officinalis regularly Pregnancy Lactation Glaucoma Hipothyroidism or Hyperthyroidism Asthma Suffering from psychosis Sensitivity to salicylates (ASA) Using antianxiety or tranquilizing drugs ten day before surgery Alcoholism

Design outcomes

Primary

Measure	Time frame
Anxiety score from Spielberger situation questionnaire. Timepoint: Pre intervention and post intervention on surgery day at 8.a.m. Method of measurement: Spielberger situation anxiety questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTabandeh Sadeghi

Rafsanjan University of Medical Sciences

t.b_sadeghi@yahoo.com+98 34 3425 5900

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026