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The effect of Malva sylvestris mouthwash on chemotherapy-induced stomatitis

Investigating the effect of Malva sylvestris mouthwash on chemotherapy-induced stomatitis in cancer patients

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150713023190N15
Enrollment
70
Registered
2024-07-20
Start date
2024-08-05
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer.

Interventions

Intervention 1: Intervention group: Patients are taught to wash their hands three times a day (after breakfast, lunch, and dinner), brush their teeth with a soft toothbrush and a mild toothpaste, and

Sponsors

Rafsanjan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 75 Years

Inclusion criteria

Inclusion criteria: Full consciousness Consent to participate in the study Confirmation of cancer Chemotherapy without concurrent radiation therapy having grade 1 to grade 3 chemotherapy-induced stomatitis History of at least one round of chemotherapy Age between 20 and 75 years No history of sensitivity to the malvaceae family Not having a mucosal lesion in the oral cavity before chemotherapy treatment Lack of pregnancy Lack of breastfeeding

Exclusion criteria

Exclusion criteria: Irregular use of mouthwash in terms of time and amount (forgetting 3 alternate days in a 14-day period completely) Using another mouthwash during the study Fever above 38/5 The patient's decision to leave the study and unwillingness to use mouthwash The occurrence of any condition that causes not to use mouthwash, such as worsening of the patient's condition, death

Design outcomes

Primary

MeasureTime frame
Stomatitis. Timepoint: Before the intervention and on the third, seventh and fourteenth days after the intervention. Method of measurement: WHO stomatitis severity checklist.;Pain. Timepoint: Before the intervention and on the third, seventh and fourteenth days after the intervention. Method of measurement: VAS pain assessment scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTabandeh Sadeghi

Rafsanjan University of Medical Sciences

t.b_sadeghi@yahoo.com+98 34 3425 5900

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026