laminectomy. Vertebral column
Conditions
Interventions
Intervention 1: Intervention 2: In Celecoxib group, 400 mg Celecoxib capsule 2 hrs before surgery and 6 hrs after surgery is given. Intervention 2: Intervention 3: In Gabapentin pulse Celecoxib group,
Treatment - Drugs
Intervention 2: In Celecoxib group, 400 mg Celecoxib capsule 2 hrs before surgery and 6 hrs after surgery is given.
Intervention 3: In Gabapentin pulse Celecoxib group, 300 mg Gabapentin capsule pulse 200 mg Celecoxib 2 hrs before surgery and 6 hrs after surgery is given.
Control 1: In placebo group, capsule contain starch 2 hrs before surgery and 6 hrs after surgery is given.
Intervention 1: In Gabapentin group, 600 mg Gabapentin capsule 2hrs before surgery and 6 hrs after surgery is given.
Sponsors
Ilam University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age 20-60; same surgeon and anesthesia. Exclusion criteria: drug abuse; history of allergic reaction to any of the study drugs; under use of non-steroidal anti-inflammatory analgesic; pregnancy; cardiovascular; metabolic; respiratory; peptic ulcer and renal failure or coagulation abnormalities.
Exclusion criteria
Exclusion criteria:
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Pruritus. Timepoint: After surgery. Method of measurement: Questionnaire.;The first movement time. Timepoint: During 24 h after surgery. Method of measurement: Questionnaire. | — |
Primary
| Measure | Time frame |
|---|---|
| Shivering. Timepoint: During recovery. Method of measurement: Checklist and VAS.;Pain. Timepoint: 2,4,6,8,12,16,24 hrs after surgery. Method of measurement: Visual Analogue Scale (VAS).;Drug consumption. Timepoint: During 24 hrs after surgery. Method of measurement: Mg. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Khani
Ilam University of Medical Sciences
Outcome results
None listed