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A comparative study of Tramadol and Lidocaine jelly effect on coughing , straining and sore throat due to tracheal tube

Comparison of Tramadol and Lidocaine and placebo jelly in 150 patients candidate for laparoscopic cholecystectomy from bucking, coughing and sore throat after endotracheal extubation.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201507114938N3
Enrollment
150
Registered
2016-02-12
Start date
2015-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

medical surveillance following treatment. Follow-up examination after surgery for other conditions

Interventions

Intervention 1: In the first group patients in the same way with propofol 2 mg / kg and midazolam 0.01 mg / kg and sufentanil 0.2 mg / kg and neuromuscular 0,5 mg / kg will put under general anesthesi
Treatment - Drugs
In the first group patients in the same way with propofol 2 mg / kg and midazolam 0.01 mg / kg and sufentanil 0.2 mg / kg and neuromuscular 0,5 mg / kg will put under general anesthesia. Isoflurane ga
In the second group patients in the same way with propofol 2 mg / kg and midazolam 0.01 mg / kg and sufentanil 0.2 mg / kg and neuromuscular 0,5 mg / kg will put under general anesthesia. Isoflurane g
In the third group patients in the same way with propofol 2 mg / kg and midazolam 0.01 mg / kg and sufentanil 0.2 mg / kg and neuromuscular 0,5 mg / kg will put under general anesthesia. Isoflurane ga
In the forth group patients in the same way with propofol 2 mg / kg and midazolam 0.01 mg / kg and sufentanil 0.2 mg / kg and neuromuscular 0,5 mg / kg will put under general anesthesia. Isoflurane ga
In the control group do not use the gel and intubation performed as usual.The patients for the occurrence of straining and cough and laryngospasm and bronchospasm will control by a person who is unawa

Sponsors

Vice chancellor for research, Kermanshah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age between 20 and 60 years; patient informed consent;patients admitted for cholecystectomy laparoscopic surgery; ASA class 1,2; mallampati 1 or 2; TMD >6cm. Exclusion criteria: history of smoking or drug abuse;a history of catching a cold in the last two weeks; patients with COPD, asthma and convulsions.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Sore throat. Timepoint: 1 and 6 and 12 hourse after extubation. Method of measurement: VAS.;Coughing. Timepoint: Immediately aftr extubation. Method of measurement: By asking of patient.;Straining. Timepoint: extubation time. Method of measurement: By asking of patient.

Secondary

MeasureTime frame
Laryngospasm. Timepoint: after extubation. Method of measurement: exist - lack.;Bronchospasm. Timepoint: after extubation. Method of measurement: exist - lack.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Rahmatinejad

kermanshah univrsity of medical science

dr_m20081362@yahoo.com+98 83 3427 6301

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026