The effect of oral Silymarin in wound healing in burns

The effect of adjuvant treatment with oral Silymarin in wound healing in burns patients admitted to the burn unit of Vali-asr Hospital, Arak, Iran

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015070923138N1

Enrollment

Registered

2016-12-26

Start date

2014-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burning. Burns of multiple regions, no more than second-degree burns mentioned

Interventions

Intervention 1: The intervention group take daily with oral 140-mg Silymarin ?. Intervention 2: Control group take under the administration of placebo.

Treatment - Drugs

The intervention group take daily with oral 140-mg Silymarin ?.

Control group take under the administration of placebo

Eligibility

Sex/Gender

All

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 18-45 years; second degree burns; burns by fire flame; reception of informed consent. Exclusion criteria: electrical burns; chemicals burns; infant and neonate; systemic disease; pregnancy; addiction; respiratory tract burns; need of intubation; Glascow coma scale less than 15; allergy to Silymarin; history of malnutrition

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain of wound of burning. Timepoint: end of week 2, 4, 6 and 8 and first and end of study?. Method of measurement: Visual Analogue Scale.;Improving wound. Timepoint: end of week 2, 4, 6 and 8?. Method of measurement: clinical response.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Shabanali alizadeh

Arak University Of Medical Sciences

m.mahmoodi@arakmu.ac.ir+98 86 3222 2003

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026