Hypotension. Hypotension due to drugs
Conditions
Interventions
Intervention 1: Intervention group-1 :Will receive 50µg Phenylephrine(group P) intravenousely after observation of hypotension episode(grater than %20 of baseline blood pressure) and in non responsive
Treatment - Drugs
Intervention group-1 :Will receive 50µg Phenylephrine(group P) intravenousely after observation of hypotension episode(grater than %20 of baseline blood pressure) and in non responsive cases ephedrine
Intervention group-2 :Will receive 5mg Ephedrine(group E) intravenousely after observation of hypotension episode(grater than %20 of baseline blood pressure) and in non responsive cases ephedrine will
Sponsors
Vce chancellor for research of Isfahan University of Medical Scienses
Eligibility
Sex/Gender
All
Age
40 Years to 65 Years
Inclusion criteria
Inclusion criteria: inclusion criteria: 110 patient with ASA physical status class I-II aged 40-65 years who are candidates of lower extremity orthopedic surgery. Exclusion criteria:Any hypersensitivity reaction to vasopressore or local anesthetic drugs, systemic diseases like cardiovascular, liver, or renal diseases and pregnancy.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systolic blood pressure. Timepoint: 2, 4, 6, 8, 10, 14, 20 and 30 minutes after arrival of the patient to the recovery room. Method of measurement: Noninvasive Blood pressure monitoring system.;Diastolic blood pressure. Timepoint: 2, 4, 6, 8, 10, 14, 20 and 30 minutes after arrival of the patient to the recovery room. Method of measurement: Noninvasive Blood pressure monitoring system.;Mean arterial blood pressure. Timepoint: 2, 4, 6, 8, 10, 14, 20 and 30 minutes after arrival of the patient to the recovery room. Method of measurement: Noninvasive Blood pressure monitoring system. | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart rate. Timepoint: 2 ?4 ? 6 ? 8 ? 10 ? 14 ? 20 and 30 minutes after arrival of the patient to the recovery room. Method of measurement: pulse oxymetery.;Arterial blood oxygen saturation. Timepoint: 2 ?4 ? 6 ? 8 ? 10 ? 14 ? 20 and 30 minutes after arrival of the patient to the recovery room. Method of measurement: pulse oxymetery.;Drug and non drug related complications. Timepoint: Any time during the study. Method of measurement: clinical evaluation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDarioush Moradi
Isfahan University of Medical Sciences
Outcome results
None listed