Role of early hemodialysis on acute kidney injury in critically ill patients

Role of early hemodialysis on acute kidney injury in critically ill patients at Tehran Imam Khomeini Hospital

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201507069045N3

Enrollment

Registered

2016-04-03

Start date

2015-09-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute renal injury.

Interventions

Intervention 1: For early Hemodialysis Group (D) , central vein catheter will be inserted for the patients and dialysis will start daily ( 2 hours for the first day then 4 hours). Dialysis will be d

Treatment - Other

For early Hemodialysis Group (D) , central vein catheter will be inserted for the patients and dialysis will start daily ( 2 hours for the first day then 4 hours). Dialysis will be done at least for

Control group: in case of oliguria (U/O<0.5 ml/kg/h) or aniria (U/O<0.3 ml/kg/h or cessation of urine ) , infusion of 500 ml crystalloid with 60 mg Furosemide in 1 hour will be administered and whi

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: if there is one of the following scales such as ; at least 50% creatinine rise from the admission time ; BUN>70 ; oliguria 100 or occurance of azotemia complications ( ex:loss of Consciousness ) and cr>4 will be specified as Group C. In case of oliguria (U/O<0.5 ml/kg/h) or aniria (U/O<0.3 ml/kg/h or cessation of urine ) , infusion of 500 ml crystalloid with 60 mg Furosemide in 1 hour will be administered and while there is no response , the patient entered the study; Exclusion criteria: history of renal insufficiency ; reception of high dose inotropics; septic shock ; severe electrolyte abnormalities leading to hemodialysis.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood urea. Timepoint: Before intervention, daily after intervention. Method of measurement: Blood sample.;Plasma creatinine. Timepoint: Before intervention, daily after intervention. Method of measurement: Blood sample.;Urine volume. Timepoint: Before intervention, daily after intervention. Method of measurement: Fully catheter and urine bag.	—

Secondary

Measure	Time frame
Length of stay in intensive care unit. Timepoint: Daily. Method of measurement: Number of admission days in intensive care unit.;Mortality rate in intensive care unit. Timepoint: Daily. Method of measurement: Rate of 28-day mortality.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Taghi Beigmohammadi.MD

Imam Khomeini Hospital Complex

mbage46@gmail.com; beigmohammadi@tums.ac.ir+98 21 6119 2511

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026