Evaluation of the effect of oral zinc in patients with chronic hemodialysis

The effect of oral zinc on nutritional and inflammatory factors in chronic hemodialysis patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150706023084N5

Enrollment

Registered

2020-04-06

Start date

2019-05-21

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Inflammation and malnutrition in patients with chronic hemodialysis.

Interventions

Intervention 1: Intervention group:The group received 2 capsules of zinc sulfate 110 mg daily along with their other medications. Intervention 2: Control group: The group received 2 placebo capsules o

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Hemodialysis patients consenting to participate in the study

Exclusion criteria

Exclusion criteria: Patients receiving tetracycline and quinolone.

Design outcomes

Primary

Measure	Time frame
HBA1C. Timepoint: Before the start of the study and three months after taking oral zinc tablets. Method of measurement: Variable serum levels were measured by chromatography.;Albumin. Timepoint: Before the start of the study and three months after taking oral zinc tablets. Method of measurement: The serum levels of the variable were measured by Bromocresol Green.;BUN or blood urea nitrogen. Timepoint: Before the start of the study and three months after taking oral zinc tablets. Method of measurement: Serum levels of variable blood were measured by tacophoresis.;Hemoglobin. Timepoint: Before the start of the study and three months after taking oral zinc tablets. Method of measurement: Serum levels of variable blood were measured by cyanometho hemoglobin.;Triglycerides. Timepoint: Before the start of the study and three months after taking oral zinc tablets. Method of measurement: The serum levels of the variable blood were measured by a special kit using triglyceride oxidase.;ESR or erythrocyte sedimentation rate. Timepoint: Before the start of the study and three months after taking oral zinc. Method of measurement: The serum level of the variable in question was measured by the Westergreen method.;Ferritin. Timepoint: Before the start of the study and three months after taking oral zinc. Method of measurement: Serum levels of variable blood were measured by RIA.;CRP or C reactive protein. Timepoint: Before the start of the study and three months after taking oral zinc. Method of measurement: Blood serum levels of the variable were measured with special latex agglutination kits.	—

Measure

Time frame

HBA1C. Timepoint: Before the start of the study and three months after taking oral zinc tablets. Method of measurement: Variable serum levels were measured by chromatography.;Albumin. Timepoint: Before the start of the study and three months after taking oral zinc tablets. Method of measurement: The serum levels of the variable were measured by Bromocresol Green.;BUN or blood urea nitrogen. Timepoint: Before the start of the study and three months after taking oral zinc tablets. Method of measurement: Serum levels of variable blood were measured by tacophoresis.;Hemoglobin. Timepoint: Before the start of the study and three months after taking oral zinc tablets. Method of measurement: Serum levels of variable blood were measured by cyanometho hemoglobin.;Triglycerides. Timepoint: Before the start of the study and three months after taking oral zinc tablets. Method of measurement: The serum levels of the variable blood were measured by a special kit using triglyceride oxidase.;ESR or erythrocyte sedimentation rate. Timepoint: Before the start of the study and three months after taking oral zinc. Method of measurement: The serum level of the variable in question was measured by the Westergreen method.;Ferritin. Timepoint: Before the start of the study and three months after taking oral zinc. Method of measurement: Serum levels of variable blood were measured by RIA.;CRP or C reactive protein. Timepoint: Before the start of the study and three months after taking oral zinc. Method of measurement: Blood serum levels of the variable were measured with special latex agglutination kits.

—

Countries

Iran (Islamic Republic of)

Contacts

Public Contacthanieh bahrami tabar

Islamic Azad University

hanieh.bahramitabar@gmail.com+98 83 4822 1456

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026