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Comparison of the palliative effect of Diphenhydramine-Almgs versus 0.1% Teriadent oral paste in patients with Recurrent Aphthous Stomatitis

Comparison of the palliative effects and stability of Diphenhydramine-Almgs versus 0.1% Teriadent oral paste in patients with Recurrent Aphthous Stomatitis

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150706023084N4
Enrollment
50
Registered
2020-01-19
Start date
2018-12-22
Completion date
Unknown
Last updated
2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recurrent Aphthous Stomatitis.

Interventions

Intervention 1: Intervention group: This group received 10 ml of the solution of mouthwash 3 times daily for one minute, then mouthwashed and avoided eating for half an hour thereafter. On the third a

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Multiple aphthous ulcers (more than 1) that appeared in the mouth less than 48 hours. People over 18 years

Exclusion criteria

Exclusion criteria: A well-known history of increased drug sensitivity Systemic diseases such as Behcet, Crohn's disease, thalassemia Vitamin B12 deficiency and iron deficiency Pregnant and lactating women smokers Taking oral antihistamine or non-steroidal anti-inflammatory drugs over the past week Aphthous ulcers adjacent to trauma caused by sharp teeth, fractured healing, orthodontic appliance or partial prosthesis

Design outcomes

Primary

MeasureTime frame
Recurrent pest as one of the most common oral mucosal diseases is a recurrent and painful disease that, due to the unclear etiology and lack of definitive treatment, requires repeated periods of treatment and use of drugs with minimal local or systemic complications. has it. Timepoint: At the beginning of the study, the third and seventh days. Method of measurement: Questionnaire and pH meter to evaluate the pH changes of the combined solution.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahtab Ghamgosar

Islamic Azad University

mhtb.gh92@gmail.com+98 13 3377 6321

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026