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Effect of vitamin c supplementation on procalcitonin biomarker in community acquired pneumonia

Comparison of the effectiveness of vitamin c supplementation on procalcitonin biomarker in community acquired pneumonia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150706023084N3
Enrollment
40
Registered
2019-10-11
Start date
2018-03-06
Completion date
Unknown
Last updated
2019-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Community acquired pneumonia.

Interventions

Intervention 1: Intervention group: This group received one vitamin C 1000 mg EFF tab daily and other medications for treating pneumonia for 10 days. Serum procalcitonin was measured and checked at th

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Diagnosis of community acquired pneumonia by physician based on clinical symptoms, chest x-rey, patients's.history and lab test results Obtaining informed consent from the patients Patients older than 18 years old in both gender.

Exclusion criteria

Exclusion criteria: Pregnancy or lactation Any hepatic or kidney failure Taking any chemothrapy medications and NSAIDs Taking antibiotics for other infectious disease at the same time

Design outcomes

Primary

MeasureTime frame
Procalcitonin(PCT) is produced in c-cells of thyroid gland as a prohormone of calcitonin. PCT has emerged as promising marker for the diagnosis of infections, because higher level of pct is found in bacterial infections than in viral infections and non specific inflammatory disease. Serum is used for measure of level of procalcitonin. Timepoint: Serum level of procalcitonin was measured at the beginning and at the end of the study(after 10 days). Method of measurement: The serum pct level was measured by VIDAS Biomerieux and pct kit, prepared by ELFA.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahsa Nikzad

Islamic Azad University

mahsanikzad74@gmail.com+98 21 6655 0318

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026