Evaluation of the effects of L-Carnitine and Coenzyme Q?? combination on DNA fragmentation index

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150706023084N23

Enrollment

Registered

2025-05-10

Start date

2025-05-05

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Male infertility with Sperm DNA Fragmentation Index (DFI) above 30. Male infertility

Interventions

Intervention 1: Intervention group: 40 infertile male patients aged over 18 years with a sperm DNA fragmentation index above 30 will be selected to participate in the study. For a duration of 3 months

Eligibility

Sex/Gender

Male

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Male gender Age above 18 years Infertility with elevated sperm DNA Fragmentation Index > 30

Exclusion criteria

Exclusion criteria: Female gender Age below 18 years Normal sperm DFI < 30 History of gastrointestinal bleding

Design outcomes

Primary

Measure	Time frame
Changes in Sperm DNA Fragmentation Index (DFI). Timepoint: Sperm DNA Fragmentation Index (DFI) assessed using the Sperm Chromatin Dispersion (SCD) test at baseline (prior to the intervention) and after 3 months. Method of measurement: Sperm Chromatin Dispersion (SCD) test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Maryam Shiehmorteza

Islamic Azad University

shiehmorteza@iaups.ac.ir+98 21 2264 0052

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026