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Evaluation of the probiotic effect of Lactobacillus reuteri in the treatment of chronic functional pain in children

Evaluation of the effectiveness of Lactobacillus reuteri probiotics in the treatment of chronic functional abdominal pain in children aged 5 to 15 years

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150706023084N14
Enrollment
180
Registered
2021-12-30
Start date
2022-01-21
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic functional abdominal pain in children. Other and unspecified abdominal pain

Interventions

Intervention 1: Intervention group: Lactobacillus reuteri probiotic. 28 sachets One gram of probiotic is dissolved in sachets of water, yogurt or food (cold) every day and consumed for 28 days. Each s

Sponsors

Faradaro Fanavar Mehr Company
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 15 Years

Inclusion criteria

Inclusion criteria: Abdominal pain is persistent or almost constant Pain has nothing to do with physiological events in the body (eating, defecation, menstruation, etc.) Some daily functions are lost The pain is not fake Symptoms to complete the criteria for other gastrointestinal functional disorders do not justify complete pain All of these criteria must be present for at least three months and the onset of symptoms at least six months before diagnosis

Exclusion criteria

Exclusion criteria: The doctor determines that the child has chronic abdominal pain due to the consumption of a certain type of food (special diet) or a specific organic problem. Existence of an underlying disease that, according to the pediatric gastroenterologist, has caused abdominal pain.

Design outcomes

Primary

MeasureTime frame
Intensity of pain. Timepoint: Every day for 28 days. Method of measurement: Based on oucher pain scale.;Frequent pain. Timepoint: Every day for 28 days. Method of measurement: Record in the table.;Duration of treatment. Timepoint: 28 days. Method of measurement: Check the questionnaire table.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Shiehmorteza

Islamic Azad University

shiehmorteza@iaups.ac.ir+98 212640056

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026