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Randomize comparison of Vaginal suppository containing zhumeria majdae essential oil with vaginal clotrimazole versus placebo vaginal suppository with vaginal clotrimazole for vulvovaginal candidiasis treatment

Randomize comparison of Vaginal suppository containing zhumeria majdae essential oil with vaginal clotrimazole versus placebo vaginal suppository with vaginal clotrimazole for vulvovaginal candidiasis treatment

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150706023084N12
Enrollment
60
Registered
2021-10-22
Start date
2021-10-05
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

candidiasis vulvovaginit. Vaginitis, vulvitis and vulvovaginitis in diseases classified elsewhere

Interventions

Intervention 1: Intervention group: It consists of 30 people, each of whom receives a 2-gram vaginal suppository containing 0.1 cc of Zhumeria maidae essential oil along with clotrimazole suppository

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: women aged 18 to 50 years Married lack of sensitivity to the plant compounds of Zhumeria majdae lack of sensitivity to clotrimazole signature the consent form to participate in the study Exclusioncriteria Diagnosis of vaginal candidiasis infection

Exclusion criteria

Exclusion criteria: pregnancy and lactation menopause underlyingdiseases forgetting a dose or more patientunwillingness to continue treatme menstruation during the study abnormal uterine bleeding sensitivity to Zhumeria majdae sensitivity to clotrimazole

Design outcomes

Primary

MeasureTime frame
Itching. Timepoint: Start of study - 7 days after the start of the study. Method of measurement: Questionnaire -Complete a checklist to evaluate the symptoms of candidal vaginitis and then compare thefrequency of symptoms of candidal vaginitis within and between the two treatment groups.;Discharge. Timepoint: Start of study - 7 days after the start of the study. Method of measurement: Questionnaire.;Inflammation. Timepoint: Start of study - 7 days after the start of the study. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSepideh Kermani

Islamic Azad University

drskermani43@gmail.com+98 81 3334 5700

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026