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Randomize comparison of vaginal suppository containing cuminum cyminum essential oil with vaginal clotrimazole versus placebo vaginal suppository for vulvovaginal candidiasis treatment

Randomize comparison of vaginal suppository containing cuminum cyminum essential oil with vaginal clotrimazole versus placebo vaginal suppository for vulvovaginal candidiasis treatment

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150706023084N11
Enrollment
60
Registered
2021-10-10
Start date
2021-10-05
Completion date
Unknown
Last updated
2021-11-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Candidiasis vulvovaginitis. Vaginitis, vulvitis and vulvovaginitis in diseases classified elsewhere

Interventions

Intervention 1: Intervention group: consist of 30 people who each receive a 2 gram vaginal suppository containing 0.1 cc of cuminum cyminum essential oil along with clotrimazole vaginal suppository da

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Women aged 18 - 50 years old Being married Signature of consent Diagnosis of candidiasis infection lack of sensitivity to cuminum cyminum or clotrimazole

Exclusion criteria

Exclusion criteria: Pregnancy lactation menopause Underlying diseases Menstruation during the study Forget one dose or more of medication Allergy to clotrimazole or cuminum cyminum suppository The patient's unwillingness to continue treatment Abnormal uterine bleeding

Design outcomes

Primary

MeasureTime frame
Itching. Timepoint: Beginning of the study - 7 days after the start of the study. Method of measurement: Questionnaire - completing a checklist to evaluate the symptoms of candidal vaginitis and then compare the frequency of symptoms of candidial vaginitis within and between the two treatment groups.;Discharge. Timepoint: Beginning of the study - 7 days after the start of the study. Method of measurement: Questionnaire.;Inflammation. Timepoint: Beginning of the study - 7 days after the start of the study. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemehSadat Abtahi

Islamic Azad University

fatemehabtahi21@yahoo.com+98 26 3460 0554

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026