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Effect of folic acid in Attention Deficit Hyperactivity Disorder

Effect of Folic acid in Children and Adolescents with Attention Deficit Hyperactivity Disorder (ADHD) Treated with Methylphenidate

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150706023083N6
Enrollment
100
Registered
2020-11-14
Start date
2020-11-02
Completion date
Unknown
Last updated
2020-11-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Attention Deficient Hyperactivity Disorder. Attention-deficit hyperactivity disorder, unspecified type

Interventions

Intervention 1: Intervention group: This group receives Folic acid (1mg/day) and methylphenidate (0.5-1 mg/kg) two to three times a day for 3 months. Methylphenidate is preferably Ritalin10 brand (man

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 12 Years

Inclusion criteria

Inclusion criteria: Diagnosis of ADHD meeting criteria according to the Diagnostic and Statistical Manual of Mental Disorders, fifth edition Stable treatment with methylphenidate Not receiving supplement before this study Age range 6-12 years old

Exclusion criteria

Exclusion criteria: Receiving supplement before this study Other psychiatric disease like autism, Chronic disease, Taking anticonvulsant Inability to understand and sign consent

Design outcomes

Primary

MeasureTime frame
Appetite. Timepoint: On arrival and after 2, 4, 6, 8, 12 weeks after receiving supplement. Method of measurement: Prepared appetite questionnaire.;Weight changes. Timepoint: On arrival and after 2, 4, 6, 8, 12 weeks after receiving supplement. Method of measurement: Scale.;Body Mass Index. Timepoint: On arrival and after 2, 4, 6, 8, 12 weeks after receiving supplement. Method of measurement: The body mass divided by the square of the body height.

Secondary

MeasureTime frame
Severity of ADHD symptoms. Timepoint: On arrival and after 2, 4, 6, 8, 12 weeks after receiving supplement. Method of measurement: Parents conners questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Haleh Rezaee

Tabriz University of Medical Sciences

rezaeeha@tbzmed.ac.ir+98 41 3337 2250

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026