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Escitalopram, fluoxetine and vitagnus in premenstrual dysphoric disorder

Comparison the effectiveness and side effects of three drugs- escitalopram, fluoxetine and vitagnus- in premenstrual dysphoric disorder

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150630022991N13
Enrollment
75
Registered
2018-10-12
Start date
2018-08-06
Completion date
Unknown
Last updated
2018-11-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Premenstrual dysphoric disorder. Other specified mood [affective] disorders

Interventions

Intervention 1: Intervention group 1: Escitalopram manufactured in Abidi´s Pharmaceutical Company 10 milligram per day for three months. Intervention 2: Intervention group 2: Vitagnus tablets manufact

Sponsors

Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Confirmed diagnosis of premenstrual dysphoric disorder To have regular menstrual periods Assignment the informed consent form of the study

Exclusion criteria

Exclusion criteria: Polycystic ovarian disease Irregular menstrual periods Psychiatric disorders: dementia, psychosis, mental retardation, opium or psychoactive drugs abuse and high mood Breast feeding

Design outcomes

Primary

MeasureTime frame
The severity of premenstrual symptoms. Timepoint: At baseline (before initiation of the intervention) and at the end of the first, second and third months after the intervention. Method of measurement: Premenstrual Syndrome Diary (PMSD) questionnaire.

Secondary

MeasureTime frame
The presence of psychologic symptoms. Timepoint: Before intervention and at the end of the third month after intervention. Method of measurement: Revised 90- Scale Symptom Checklist (SCL-90-R).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSussan Moudi

Babol University of Medical Sciences

sussan.mouodi@mubabol.ac.ir+98 11 3236 5683

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026