epilepsy. Nonspecific epileptic seizures:•atonic
Conditions
Interventions
Intervention 1: Standard treatment plus 300 mg (one tablet) omega-3 twice a day orally for 4 months. Intervention 2: Standard treatment plus a placebo tablet twice daily orally for 4 months.
Treatment - Drugs
Placebo
Standard treatment plus 300 mg (one tablet) omega-3 twice a day orally for 4 months
Standard treatment plus a placebo tablet twice daily orally for 4 months
Sponsors
hamadan university of medical sciences, Vice-chancellor for research and technology , Hamedan
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: drug resistant epilepsy; 18 to 65 years old. Exclusion criteria: patients with impaired renal function; patients with catamenial seizure; Patients with hepatic dysfunction; Patients with active infection; Patients with brain or mental dysfunction; Patients who can not take oral medication; Patients treated with anti-inflammatory or antioxidant drugs in the past month; patients with other concurrent inflammatory disease; Patients who can not tolerate the side effects; Patients who are pregnant or lactating
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The frequency of attacks. Timepoint: Up to 4 months after the start treatment. Method of measurement: Quantitatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| IL-6. Timepoint: Before the intervention-4 months after the treatment. Method of measurement: pg per ml by ELISA.;TNF-a. Timepoint: Before the intervention-4 months after the treatment. Method of measurement: pg per ml by ELISA. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Rasool Haddadi
Hamadan university of medical sciences, Faculty of pharmacy
Outcome results
None listed