Effect of grape seed extract on denture stomatitis

Comparison of the effects of Grape seed extract and Nystatin mouthwash on denture stomatitis

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150628022951N6

Enrollment

Registered

2018-09-05

Start date

2018-10-12

Completion date

Unknown

Last updated

2018-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Denture Stomatitis. Stomatitis and related lesions

Interventions

Intervention 1: Intervention group: Rinse out 20 drops of grape seed extract every 8 hours. Intervention 2: Control group: Rinse out 20 drops of nystatin every 8 hours.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Suffering denture stomatitis erythematous Having a healthy denture without leaping and discoloration

Exclusion criteria

Exclusion criteria: Use of anti-fungal drugs, antibiotics and corticosteroids in the past month Allergy to nystatin and grape seed extract

Design outcomes

Primary

Measure	Time frame
Dimensions of denture stomatitis. Timepoint: Pre-intervention, 5,10,15, 20 days after intervention. Method of measurement: Measuring the length and width of the erythema with a digital ruler.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Hossein Eslami

Tabriz University of Medical Sciences

eslamihosein56@yahoo.com+98 41 3335 9680

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026