Preoperative administration of oral pregabalin for reducing pain in patients with mandibular fractures

Comparison of pain relief efficacy of pre empetive intravenous ketorolac and oral pregabalin in patients undegoing mandibular fracture surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150628022951N10

Enrollment

Registered

2019-07-22

Start date

2019-07-23

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain. Acute pain due to trauma

Interventions

Intervention 1: Control group: Intra-venous injection of a 30-mg dose of ketorolac (Caspian Pharmaceutical Company, Iran) one hour before induction of anesthesia. Intervention 2: Intervention group :

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with unilateral mandibular fracture in the body and angle region, with fracture occurring not more than two weeks ago

Exclusion criteria

Exclusion criteria: Addicted patients

Design outcomes

Primary

Measure	Time frame
Pain Intensity. Timepoint: Immediately after consciousnesses and 2, 4, 6, 8, 12, 24 hours after surgery. Method of measurement: Visual Analogue Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJavad Yazdani

Tabriz University of Medical Sciences

Ja_yazdani@yahoo.com+98 41 3336 4658

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026