Ginger effect on osteoarthritis of the knee

Comparison of the effect of ginger skin patch and oral capsule on pain severity, stiffness and daily functioning in patients with osteoarthritis of the knee

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015062722929N1

Enrollment

120

Registered

2015-08-25

Start date

2015-07-11

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthrities Of Knee. Gonarthrosis[arthrosis Of Knee]

Interventions

Intervention 1: The first group, will receive a daily skin patch in the mid-lumbar region for 13 weeks, In addition to their standard treatment. This is a skin patch containing one gram of ginger. Int

Treatment - Drugs

The first group, will receive a daily skin patch in the mid-lumbar region for 13 weeks, In addition to their standard treatment. This is a skin patch containing one gram of ginger.

The third group is the control group. In this group, only standard medication that is prescribed by orthopedic specialist receive. Intervention is not done.

The second group will receive two capsules daily for 13 weeks, in addition to standard treatment. Each capsule contains 500 mg of ginger.

Eligibility

Sex/Gender

All

Age

50 Years to No maximum

Inclusion criteria

Inclusion criteria: inclusion criteria: The approval of osteoarthritis of the knee by orthopedic specialist; 50 years and older; Lack of regular use of ginger or sensitivity to it; No injection in the joint or joint surgery for at least 6 months ago; Lack of Rheumatism, Diabetes, Cancer, Alzheimer's and Schizophrenia; No wound in mid-lumbar region. Exclusion criteria: Not consent to continue study; Failure to comply with the study protocol; The incidence of adverse events in each of the samples.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain severity. Timepoint: Before, during intervention, a week after intervention. Method of measurement: Using a visual scale pain.;Joint stiffness. Timepoint: Before, during intervention, a week after intervention. Method of measurement: Western Ontario and Mc Master Universities Questionnaire.;Daily performance. Timepoint: Before, during intervention, a week after intervention. Method of measurement: WOMAC Questionnaire.	—

Measure

Time frame

Pain severity. Timepoint: Before, during intervention, a week after intervention. Method of measurement: Using a visual scale pain.;Joint stiffness. Timepoint: Before, during intervention, a week after intervention. Method of measurement: Western Ontario and Mc Master Universities Questionnaire.;Daily performance. Timepoint: Before, during intervention, a week after intervention. Method of measurement: WOMAC Questionnaire.

—

Secondary

Measure	Time frame
Analgesic dose. Timepoint: Before the study, during the study and after study. Method of measurement: Using a questionnaire prepared by the researcher.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Marzieh Asadizaker

School of Nursing and Midwifery, Ahwaz University of Medical Sciences

marziyehasadizaker@yahoo.com00

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026