Ovulation induction. Female infertility associated with anovulation
Conditions
Interventions
Intervention 1: In the letrozole group, letrozole 2.5 mg BID was given for 5 days from day 3 of their menstrual cycle. In addition, all the patients received a daily intramuscular HMG. The dosage was
Treatment - Drugs
In the letrozole group, letrozole 2.5 mg BID was given for 5 days from day 3 of their menstrual cycle. In addition, all the patients received a daily intramuscular HMG. The dosage was 75 IU starting o
The patients in the clomiphene + HMG group received clomiphene citrate 50 mg twice a day (BID) for 5 days starting from day 3 of their menstrual cycle. In addition, all the patients received a daily i
Sponsors
Research Faculty of Mashhad University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Inclusion criteria: infertility; resistance to 3 cycle clomiphene therapy; candidate for IUI Exclusion criteria: no consent for participation
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Follicles size. Timepoint: the days 3, 9, 12 of the cycle. Method of measurement: Transvaginal ultrasonography.;Endometrial thickness. Timepoint: after clomiphene + HMG and letrozole + HMG. Method of measurement: By transvaginal ultrasonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fertility rate. Timepoint: 2 weeks after IUI. Method of measurement: by positive hCG.;Fertility rate. Timepoint: 2 weeks after IUI. Method of measurement: by positive hCG. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactTooran Makhdoumi
Ghaem Hospital
Outcome results
None listed