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Efficacy of antibiotic prophylaxis during extracorporeal shock wave lithotripsy in prevention of urinary tract infections in patients with urine proven sterile prior to treatment

Efficacy of antibiotic prophylaxis during extracorporeal shock wave lithotripsy(ESWL) in prevention of urinary tract infections in patients with urine proven sterile prior to treatment

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015062422897N1
Enrollment
150
Registered
2015-11-25
Start date
2015-06-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

UTI. Calculus of kidney and ureter

Interventions

Intervention 1: Patients are divided into two groups of A and B. Group A (the intervention group) will be given 200 mg of Ofloxacin every 12 hours. Intervention 2: Group B ( control group) will be giv
Treatment - Drugs
Placebo
Patients are divided into two groups of A and B. Group A (the intervention group) will be given 200 mg of Ofloxacin every 12 hours.
Group B ( control group) will be given placebo which is a pill made from flour.

Sponsors

Babol University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: minimum age 18 years; negative urine culture before ESWL; absence of Foley catheter or nephrostomy tube; no history of infectious stones. Exclusion criteria: patients who have not had suitable follow up; those who have done urine culture in the 2 weeks after ESWL; manipulation of the urinary system during and after ESWL.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The incidence of urinary tract infections was measured among patients without risk factors. Timepoint: Urine analysis was performed 5 days before ESWL surgery. Method of measurement: Calculate number organisms in the urine according to CFU.

Secondary

MeasureTime frame
Increased antibiotic resistance and drug side effects and interactions compared with placebo has occurred. Timepoint: monthly. Method of measurement: Urine culture and physical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Shafie

Babol University of Medical Sciences

dr_hamidshafi@yahoo.com+98 11 3219 2832

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026