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Treatment of candida vaginitis

Comparison of the effect of 15ppm silver nanoparticles spray (Nivasha) and clotrimazole cream in the treatment of candida vaginitis

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150624022896N2
Enrollment
100
Registered
2022-01-03
Start date
2021-12-22
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

candida vaginitis.

Interventions

Intervention 1: Intervention group: Nivasha spray containing 50 cc solution of silver nanoparticles with a concentration of 15 ppm for 10 consecutive days and once a day and 3 puffs each time is pres

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 49 Years

Inclusion criteria

Inclusion criteria: Women of childbearing age 15-49 years Married women Consent to participate in the study Be literrat No pregnancy No breast feeding and menopause Having 2 symptoms of candida vaginitis (vaginal discharge, itching) Healthy women (without known immunosuppressive disease, hypertension, diabetes mellitus) Don’t use of herbal and chemical drugs for vaginitis during recent 2 weeks No other vaginal infections such as trichomoniasis Don’t use of any vaginal cream 48 hours before onset of study No participation in another study at the same time as the present study Do not use antibiotics and corticosteroids for the past two weeks No report of allergy to Nivasha spray (containing silver) (if used previously) and clotrimazole (if used previously) Getting Candida Vaginitis for the First Time

Exclusion criteria

Exclusion criteria: Mensturation at onset of study AUB Antibiotice use for systemic infections during study

Design outcomes

Primary

MeasureTime frame
Vulvar itching. Timepoint: Every day for 10 days. Method of measurement: Vaginal exam - Self report.;Vulvar redness. Timepoint: Every day for 10 days. Method of measurement: Vaginal exam - Self report.;White cheese discharge. Timepoint: Every day for 10 days. Method of measurement: Vaginal exam - Self report.

Secondary

MeasureTime frame
Vulvar edema. Timepoint: Every day for 10 days. Method of measurement: Vaginal exam - self report.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Kianpour

Esfahan University of Medical Sciences

kianpour@mail.mui.ac.ir+98 31 3792 7609

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026