The comparission of EMLA cream and vapocoolant spray in reducing pain and anxity in catheterization

Comparison of the effect of Vapocoolant spray and EMLA cream in reduction of pain and anxiety caused by venipuncture in 6-12 years old children with Thalassemia in Tehran thalassemia center

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015062222815N2

Enrollment

Registered

2015-11-19

Start date

2015-07-06

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain during Venupuncture. During aspiration, puncture and other catheterization

Interventions

Intervention 1: First in group one, the catheterization is done without any intervention, then before second catheterization used from EMLA Cream and then Vapocoolant Spray. Intervention 2: First in g

Treatment - Other

First in group one, the catheterization is done without any intervention, then before second catheterization used from EMLA Cream and then Vapocoolant Spray

First in group two, the catheterization is done without any intervention, then before second catheterization used from Vapocoolant Spray and then EMLA Cream.

Eligibility

Sex/Gender

All

Age

6 Years to 12 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria: 6-12 years old children with major thalassemia registered in thalassemia center; Full consciousness and fluency the Persian language to communicate appropriately and the ability to communicate verbally; Not using analgesics and anti anxiety agents Exclusion Criteria: Any acute side effects related to the interventions

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: In three phases: without intervention, after EMLA Cream and after Vapocoolant Spray application. Method of measurement: Visuale analoge Scale.	—

Secondary

Measure	Time frame
Anxiety. Timepoint: In three phases: without intervention, after EMLA Cream and after Vapocoolant Spray application. Method of measurement: Visuale analoge Scale for Anxiety.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Hatamizadeh

University of Social Welfare and Rehabilitation Sciences

maryamhatamizadeh@gmail.com+98 21 2218 0036

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026