lichen planus. Other lichen planus
Conditions
Interventions
Intervention 1: zinc sulfate 250mg
twice a day
for 8 week. Intervention 2: placebo
zinc capsule without content
twice a day
8 week.
Treatment - Drugs
Placebo
zinc sulfate 250mg
twice a day
for 8 week
placebo
zinc capsule without content
twice a day
8 week
Sponsors
Shiraz University of Medical Sciense
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: inclusion criteria: symptomatic oral lichen planus exclusion criteria:lichenoid reactions;immune deficiency ; consumption of medications that affect serum zinc level ; mal-absorption disorder ;The factor that changes the absorption of zinc(pregnancy ,lactation, iron and calcium supplement) ;alcoholism ; drug therapy for lichen planus for 2 last month ; acute phase of post surgery ;malignancy;Patients who are not willing to participate in the study ;smoking ; sensitivity to zinc ;consumption of systemic steroids
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Healing of oral lesion. Timepoint: 2 week-2 month-3month. Method of measurement: size of lesion- oral extension- type of disease- pain level. | — |
Secondary
| Measure | Time frame |
|---|---|
| Recurency. Timepoint: 2 and 3 month. Method of measurement: recurency period. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFahimeh Rezazadeh
Shiraz Dental School
Outcome results
None listed