Deep Vein Thrombosis. Phlebitis and thrombophlebitis of other deep vessels of lower extremities
Conditions
Interventions
Intervention 1: Control group: Patients are being treated with warfarin. Drug daily intake of 5 to 10 mg with the goal of maintaining an INR level of 2-3. Intervention 2: Intervention group: Rivaroxab
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: All patients with unilateral Deep Vein thrombosis of the lower extremities.
Exclusion criteria
Exclusion criteria: Patients with ESRD who underwent regular dialysis and patients with CRF who had GFR below 1.73 m2.mL / min Patients need any invasive intervention in the treatment of DVT. The patient with any illness, including infection and sepsis, which can interfere with the level of inflammatory factors and D-dimer. Patients with history of active malignancy. Bilateral lower limb DVT
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of post thrombotic phlebitis syndrome. Timepoint: After three months from the start of the study. Method of measurement: Based on clinical criteria according to Brandjes questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum levels of C-reactive protein, D-Dimer, as well as lower limb size. Timepoint: At the end of the third month of study. Method of measurement: Using serum samples to measure serum CRP and D-dimer levels, as well as instrumentation for measuring lower limb size. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mehdi Pishgahi
Shahid Beheshti University of Medical Sciences
Outcome results
None listed