The efficacy of different doses of tranexamic acid on amount of bleeding and duration of surgery in sinus endoscopy

Comparison the efficacy of different doses of tranexamic acid on amount of bleeding and duration of surgery in sinus endoscopy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015062021436N2

Enrollment

100

Registered

2015-07-07

Start date

2015-07-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bleeding, sinus. Antepartum haemorrhage, unspecified

Interventions

Intervention 1: First group:infusion of 5mg/kg tranexamic acid. Intervention 2: Second group :infusion of 10mg/kg tranexamic acid.

Prevention

First group:infusion of 5mg/kg tranexamic acid

Second group :infusion of 10mg/kg tranexamic acid

Eligibility

Sex/Gender

All

Age

16 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: all patients 16 to 60 years old with ASA I,II are undergoing sinus endoscopy with no airway complications, systemic diseases or known psychological diseases surgery Patients had no history of sensitivity to anesthesia or any other drugs used in this study. Exclusion criterion: the time of operation takes more than 150 minutes.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Bleeding. Timepoint: 15, 30, 60, 90, 120 and 150 minutes after surgery. Method of measurement: Boezaart scale.;Duration of surgery. Timepoint: At the end of surgery. Method of measurement: Minute.;Surgeon satisfaction. Timepoint: At the end of surgery. Method of measurement: Likertt scale.	—

Countries

Iran (Islamic Republic of)

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026