Atopic dermatitis with mild to moderate sevirty (SCORAD below than 12)). Atopic dermatitis
Conditions
Interventions
Intervention 1: Intervention: Linola F® cream, twice a day at the site of disease (Only one side of the body, one hand or one foot). Intervention 2: Control: moisturizing routine in the opposite le
Treatment - Drugs
Intervention: Linola F® cream, twice a day at the site of disease (Only one side of the body, one hand or one foot)
Control: moisturizing routine in the opposite lesion
Sponsors
Sina Tejart Pishgam® company
Eligibility
Sex/Gender
All
Age
2 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion Criteria: Case of Mild to moderate atopic dermatitis Aged (>2) years old At least 2 lesions on arms or legs with identical local SCORAD Written Informed Consent Having a negative pregnancy test Willingness to actively participate in the study and to come to the scheduled visits respectively willingness of parents/legal guardians to actively participate in the study and to come to the scheduled visits Willingness to discontinue the use of any conventional skin care products (e.g. creams, lotions, sunscreens) at the treatment areas of Linola F throughout the course of the study Exclusion Criteria: Pregnancy or lactation Severe Atopic eczema (local SCORAD >12) Drug addicts, alcoholics One of the following serious illnesses, if not medicated: cardiovascular diseases, asthma, hypertension Active skin disease at test area (except atopic dermatitis) Moles, tattoos, scars, hairs, dark pigmentation etc. at the test area that could influence the investigation Documented allergies to cosmetic products History of HIV History of Hepatitis C History of Hepatitis B Being involved in any other research project /clinical trial
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Trans Epidermal Water Loss(TEWL). Timepoint: Visit 0, 2 week after Visit 0, 4 week after Visit 0. Method of measurement: MPA.;Corneometer. Timepoint: Visit 0, 2 week after Visit 0, 4 week after Visit 0. Method of measurement: MPA. | — |
Secondary
| Measure | Time frame |
|---|---|
| SCORAD Measure. Timepoint: Visit 0, 2 week after Visit 0, 4 week after Visit 0. Method of measurement: SCORAD.;Burning, Iching, Temperature, Sebum, PH ,Mexameter. Timepoint: v. Method of measurement: MPA, calculating measures.;Thickness , Density. Timepoint: Visit 0, 2 week after Visit 0, 4 week after Visit 0. Method of measurement: Ultrasonography.;Satisfaction with the solution treatment. Timepoint: 2 week after Visit 0, 4 week after Visit 0. Method of measurement: questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Alireza Firooz
Centre for Research and Training in Skin Diseases and Leprosy
Outcome results
None listed