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Decreasing pain in prostate surgery

To evaluate the effect of intracapsular bupivacaine injection in post open prostatectomy pain control

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015061822168N2
Enrollment
38
Registered
2015-12-21
Start date
2015-07-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign prostatic hyperplasia. Hyperplasia of prostate

Interventions

Intervention 1: In the intervention group after removing the prostatic adenoma, 20 ml of 0.5% bupivacaine will be injected in the posterior prostatic capsule from 4 to 8 o clock. Intervention 2: In th
Prevention
Placebo
In the intervention group after removing the prostatic adenoma, 20 ml of 0.5% bupivacaine will be injected in the posterior prostatic capsule from 4 to 8 o clock.
In the control group after removing the prostatic adenoma, 20 ml of normal saline will be injected in the posterior prostatic capsule from 4 to 8 o clock.

Sponsors

Vice chancellor for research, Jundishapur University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
55 Years to 100 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients who are candidate for open prostatectomy due to obstructive urinary symptom and do not have allergy to bupivacaine Exclusion criteria: Prostatic capsule perforation during the surgery

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
The amount of pethidine used. Timepoint: Every our in the first 8 hours from the surgery and then every 3 hours therafter up to 24 hours. Method of measurement: The amount of used drug in miligram.;Amount of pain. Timepoint: Every our in the first 8 hours from the surgery and then every 3 hours therafter up to 24 hours. Method of measurement: Based on pain visual analog scale which is filled by the patient from 0 to 10.

Secondary

MeasureTime frame
Side effects. Timepoint: 24 hours after the surgery. Method of measurement: Any changes in blood pressure and cardiac arrhythmias.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Dinyar Khazaeli

Ahvaz Jundishapur University of Medical Sciences

khazaeli_dinyar@yahoo.com ; khazaeli-d@ajums.ac.ir+98 61 3222 2114

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026