infertility. Female infertility associated with anovulation,Female infertility of tubal origin,Female infertility associated with male factors,Female infertility of other origin,Female infertility, unspecified,
Conditions
Interventions
Intervention 1: In the intervention group for final oocyte maturation use of 5000 IU HCG intramuscular with 0.2 mg subcutaneous Decapeptyl(GNRH-agonist). Intervention 2: In the control group patient
Treatment - Drugs
In the intervention group for final oocyte maturation use of 5000 IU HCG intramuscular with 0.2 mg subcutaneous Decapeptyl(GNRH-agonist)
In the control group patients receive 10000IU HCG for final oocyte maturation
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: inclusion criteria: age18-40 years;regular mense(25-34 days);BMI between 18-35;FSH days 3 =10;AMH==16 follicles on the last trans vaginal sonography );endocrine deases(DM ,hyperprolactinemia,thyroide dysfunction ,CAH,cushing syndrome);PCOs;uterine anomaly in HSG or hysteroscopy;sever male factor(azospermia require to TESE or PESA);history of OHSS;criteria of ovarian hyper response or ovarian poor response
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of Metaphase II oocyte. Timepoint: on oocyte retrieval day. Method of measurement: evaluation by embryologist under microscope.;Number of Metaphase II oocytse ,total number of oocytes,number of embryoss. Timepoint: oocyte retrieval day,day3 after oocyte retrieval or IVF. Method of measurement: evaluation under microscope by an embryologist and scoring by scientific evidence. | — |
Secondary
| Measure | Time frame |
|---|---|
| Biochemical pregnancy ,clinical pregnancy,abortion ,OHSS. Timepoint: two weeks after transfer for biochemical pregnancy,4weeks for clinical pregnancy,2 weeks after transfer for OHSS. Method of measurement: BHCG for biochemical ,trans vaginal sonography for clinical,clinical evaluation for OHSS. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMarzieh Ghasemi
Tehran University of Medical Sciences,infertility ward
Outcome results
None listed