Effect of inhalation aromatherapy with lavender and chamomile essential oils versus acetaminophen on post adenotonsillectomy pain in children

Effect of inhalation aromatherapy with lavender and chamomile essential oils versus acetaminophen on post adenotonsillectomy pain in children: a triple blind randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201506159014N70

Enrollment

144

Registered

2015-06-18

Start date

2015-07-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tonsillitis. Chronic tonsillitis

Interventions

Intervention 1: Lavender essential oils 1%, 3 drops every 6 hours during the first 24 hours and then, every 8 hours for the next 48 hours through inhalation plus oral acetaminophen 10 to 15 mg/kg. Int

Treatment - Drugs

Placebo

Lavender essential oils 1%, 3 drops every 6 hours during the first 24 hours and then, every 8 hours for the next 48 hours through inhalation plus oral acetaminophen 10 to 15 mg/kg.

Chamomile essential oils 1%, 3 drops every 6 hours during the first 24 hours and then, every 8 hours for the next 48 hours through inhalation plus oral acetaminophen 10 to 15 mg/kg

Lavender and chamomile compound essential oils 1%, 3 drops every 6 hours during the first 24 hours and then, every 8 hours for the next 48 hours through inhalation plus oral acetaminophen 10 to 15 mg/

Distilled water 3 drops every 6 hours during the first 24 hours and then, every 8 hours for the next 48 hours through inhalation plus oral acetaminophen 10 to 15 mg/kg

Eligibility

Sex/Gender

All

Age

5 Years to 12 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: (a) age of 5 to 12 years; (b) candidate for adenotonsillectomy. Exclusion criteria: (a) history of allergy; (b) sensitivity to ethers and aromatic compounds; (c) history of asthma; (d) severe bleeding during operation; (e) using analgesic during operation.

Exclusion criteria

Exclusion criteria:

Design outcomes

Secondary

Measure	Time frame
Assessing nausea and vomiting. Timepoint: every 6 hours for 3 days. Method of measurement: through question from the patient.;Assessing bleeding form the operational location. Timepoint: every 6 hours for 3 days. Method of measurement: through physical examination.	—

Primary

Measure	Time frame
Assessing the pain on the operational location. Timepoint: every 6 hours for 3 days. Method of measurement: using visual analog scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mohammad Alipoor

Besat Hospital

dralipour76@yahoo.com+98 81 3364 0030

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026