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The Effect of Phytochemicals on the treatment of Phlebitis

The effect of Quercetin and Tannic acid on the treatment of phlebitis caused by venous catheters

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2015061422738N1
Enrollment
120
Registered
2016-01-17
Start date
2015-10-23
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

phlebitis. Vascular complications following infusion, transfusion and therapeutic injection

Interventions

Intervention 1: Use of Placebo (cream base) in the control group for 72 hours in 12-hour intervals in the area of phlebitis. Intervention 2: Use of Tannic acid 7% in intervation group for 72 hours i
Placebo
Treatment - Drugs
Use of Placebo (cream base) in the control group for 72 hours in 12-hour intervals in the area of phlebitis
Use of Tannic acid 7% in intervation group for 72 hours in 12-hour intervals in the area of phlebitis
Use of Quercetin 2% in intervation group for 72 hours in 12-hour intervals in the area of phlebitis
Use the combination of Quercetin 2% and Tannic acid %7 in an intervention group for 72 hours in 12-hour intervals in the area of phlebitis

Sponsors

Deputy of Research and Technology, Birjand University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: IInclusion criteria: having an IV catheter, gauge No. 20 (with all catheters of an essentially single brand), age between 18-60 years old, hospitalization in the internal medicine ward for at least 72 hours, no allergy to the drugs and the wound dressing, lack of blood transfusion, systolic blood pressure between 90 to 180 mmHg, no diabetes, no skin disease in the area of phlebitis, no pregnancy or lactation, having at least one phlebitis symptom (pain, redness, irritation) around the area, no chemical or herbal oil use for treatment of the phlebitis during the study, no history of allergy to the plants containing Quercetin or Tannic acid, using upper limbs for catheterization, using aseptic conditions for catheterization Exclusion criteria: patients discharged before three days, taking contraceptive drugs, patients with known comorbidities including hyper-coagulability states (e.g., anti-cardiolipin antibodies, anti-phospholipid antibodies, and vitamin C deficiency)

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Phlebitis. Timepoint: Before and 12 hours after treatment for 72 hours. Method of measurement: 4 degree visual phlebitis scale.

Secondary

MeasureTime frame
Dermal side effects. Timepoint: 12 hours for 72 hours. Method of measurement: Observation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohsen Foadoddini

Birjand University of Medical Sciences

foadmohsen@yahoo.com foadoddini@bums.ac.ir+98 56 3239 5861

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026