Prevention of contrast nephropathy in patients undergoing coronary angiography or angioplasty

Effect of preparation trough non-regional induced ischemia in the prevention of contrast medium nephropathy in patients undergoing coronary angiography or angioplasty

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015061422713N1

Enrollment

Registered

2015-06-30

Start date

2013-04-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Contrast medium Nephropathy. Nephropathy induced by unspecified drug, medicament or biological substance

Interventions

Intervention 1: Intervention group: Angiogram or angioplasty patients who after angiography or angioplasty in 4 times receive induction of ischemic limbs after angiography or angioplasty in 4 times. I

Prevention

Intervention group: Angiogram or angioplasty patients who after angiography or angioplasty in 4 times receive induction of ischemic limbs after angiography or angioplasty in 4 times.

Control group: Patients who received Normal Saline in 1.5 CC for a kilogram in an hour, during 3 to 12 hours before and 6 to 24 hours after angiography or angioplasty.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: The patients undergoing angiography or angioplasty due to elevated acute coronary syndrome (Non-ST Elevation Myocardial Infarction); Patients who have risk score more than 6, based on Mehran studies. Exclusion criteria: Patients undergoing ST Elevation Myocardial Infarction; Patients undergoing cardiogenic shock; Patients with severe heart failure (NYHA class 3 or 4, or left ventricular ejection fraction less than 30%) that do not tolerate mentioned protocol of treatment fluid; Kidney transplant patients or patients undergoing dialysis; Patients who receive contrast cronary substance a week before angiography or angioplasty; Patients who can not stand cuff inflation for 5 minutes; Patients with bleeding disorders so that they suffered at least 1 gram per deciliter Hb falling.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Failure caused by Contrast medium (CIN). Timepoint: 24 to 48 hours after angiography or angioplasty. Method of measurement: Blood test.;Blood creatinine level. Timepoint: 24 to 48 hours after angiography or angioplasty. Method of measurement: Blood test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Mesoud Sajadi

Imam Reza Hospital

s.masoud.sajjadi@gmail.com+98 51 3841 4499

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026