The effect of remote ischemic preconditioning in patients with acute myocardial infarction

A clinical trial to compare the effectiveness of remote ischemic preconditioning and primary coronary percutaneous intervention on cardiovascular outcomes in patients with acute myocardial infarction

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150614022713N2

Enrollment

Registered

2018-11-29

Start date

2018-12-22

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myocardial infarction. Acute myocardial infarction

Interventions

Intervention 1: Intervention group: The intervention group will receive remote ischemic preconditioning. In this method, a blood pressure cuff is fastened on one of the patient's organs before surgery

Eligibility

Sex/Gender

All

Age

20 Years to No maximum

Inclusion criteria

Inclusion criteria: Age higher than 20 years An elapse of 12 hours form the primary diagnosis

Exclusion criteria

Exclusion criteria: Thrombolysis in myocardial infarction (TIMI) score of 2-3 Rentrop grade of >1 Need for coronary artery bypass graft Cardiogenic shock

Design outcomes

Primary

Measure	Time frame
Major adverse cardiovascular events (i.e., mortality, second myocardial infarction, and stroke during admission). Timepoint: Before and 24 hours after the intervention. Method of measurement: Echocardiography.;The reduction of ST-segment as an indicator of microvascular reperfusion. Timepoint: Before and 24 hours after the intervention. Method of measurement: Electrocardiogram (ECG).;Thrombolysis in myocardial infarction flow. Timepoint: Before and 24 hours after the intervention. Method of measurement: Thrombolysis in Myocardial Infarction (TIMI) flow.	—

Measure

Time frame

Major adverse cardiovascular events (i.e., mortality, second myocardial infarction, and stroke during admission). Timepoint: Before and 24 hours after the intervention. Method of measurement: Echocardiography.;The reduction of ST-segment as an indicator of microvascular reperfusion. Timepoint: Before and 24 hours after the intervention. Method of measurement: Electrocardiogram (ECG).;Thrombolysis in myocardial infarction flow. Timepoint: Before and 24 hours after the intervention. Method of measurement: Thrombolysis in Myocardial Infarction (TIMI) flow.

—

Secondary

Measure	Time frame
Cardiac enzymes. Timepoint: Before and 24 hours after the intervention. Method of measurement: Blood test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMasoud Sajjadi

Mashhad University of Medical Sciences

sajjadim961@mums.ac.ir+98 51 3854 3031

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 21, 2026