chronic rhinosinusitis with nasal polyposis. Other polyp of sinus Polyp of sinus: accessory ethmoidal maxillary sphenoidal
Conditions
Interventions
one intervention group which includes conventional treatment for chronic rhinosinusitis with nasal polyposis including intranasal beclomethasone one puff in each nostril twice per day, nasal saline ri
Treatment - Drugs
Sponsors
Vce chancellor for research of Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age 18-65 years old; presence of symptoms of chronic rhinosinusitis with nasal polyps which is documented on CT scan. Exclusion criteria: existence of any serious underlying disease such as bleedin tendency, gastrointestinal, rheumatologic, malignancy, cardiac, renal, hepatic, psychological; history of IgE mediated reactions to aspirin or nonsteroidal anti inflammatory drugs; first second expiratory volume of more than 70 percent of predicted before aspirin challenge test; pregnancy; breast feeding; use of topical and systemic beta blockers; use of warfarin and warfarin derivates; mastocytosis; patients with poor cooperation and poor adherence.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of symptoms of chronic rhinosinusitis with nasal polyposis. Timepoint: after 3 months. Method of measurement: Sino Nasal Outcome Test (SNOT) questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Complications of conventional treatment including epistaxis, nasal burning sensation, nasal septal perforation, feeling sleepy. Timepoint: before intervention, three months after intervention. Method of measurement: history taking. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSima Shokri
Iran University of Medical Sciences
Outcome results
None listed