Condition 1: Acute pain. Condition 2: Nausea and vomiting. Acute pain, not elsewhere classified Nausea and vomiting
Conditions
Interventions
Intervention 1: Intervention group: In the intervention group, dexmedetomidine vial made by Hospira Co. with the brand name of Precedex, Will be administered intravenously with an induction dose of 1
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Patients between the ages of 18 and 40 Patients with skeletal class 3 deformity who are candidates for bimaxillary orthodontic surgery (maxillary advancement using Lefort 1 osteotomy and mandibular setback surgery by bilateral sagittal split osteotomy (BSSO)) Patients with a Body Mass Index of less than 30 kg / m2 Patients who have completed the informed consent
Exclusion criteria
Exclusion criteria: Patients with a history of drug allergy Patients with a history of Motion Sickness Patients with a history of addiction or psychological problems Patients with a history of hypotension and bradycardia Patients with upper gastrointestinal problems such as gastric ulcer, reflux, pyloric stenosis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain degree. Timepoint: 1 hour, 3 hours, 6 hours, 12 hours, and 24 hours postoperatively. Method of measurement: Visual analogue scale (VAS) for pain.;Presence or absence of nausea. Timepoint: Immediately after recovery and 1 hour, 3 hours, 6 hours, 12 hours, and 24 hours postoperatively. Method of measurement: scoring (0=non, 1=nausea).;Presence or absence of vomiting. Timepoint: Immediately after recovery and 1 hour, 3 hours, 6 hours, 12 hours, and 24 hours postoperatively. Method of measurement: scoring (0=non, 1=vomiting, 2=vomiting >2 times). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSahand Samieerad
Mashhad University of Medical Sciences
Outcome results
None listed