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Evaluating the effect of Montelukast on pain following orthognathic surgery.

Evaluating the effect of pre-operative administering of oral Montelukast on the pain amount following orthognathic surgery.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150613022697N8
Enrollment
60
Registered
2020-12-02
Start date
2020-10-21
Completion date
Unknown
Last updated
2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain in Jaws. Disease of jaws, unspecified

Interventions

Intervention 1: Intervention group: One dose of 10 mg oral montelukast tablet ( made by Abidi pharmaceutical company under the brand name Airokast) will be dissolved in 20cc of apple juice and will b

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Patients suffering from skeletal class 3 deformity, requiring advancement of the maxilla and set back of mandible using Lefort 1 and BSSO (Bilateral Sagittal Split Osteotomy ) technique respectively. Patients between 18 to 40 years old. Patients who are categorized in the 1st and 2nd group according to the ASA (American Society of Anesthesiology ) Patients who completed the informed consent.

Exclusion criteria

Exclusion criteria: Patients with a history of using analgesics or psychiatric medication during the previous month. Patients with a history of addiction or psychological problems . Patients with a history of drug allergy. Patients with a history of severe sinusitis .

Design outcomes

Primary

MeasureTime frame
Amount of pain in the specified time period. Timepoint: 1 hour before the surgery and also 1 ,3 ,6 , 12 , 18 ,and 24 hours after the surgery. Method of measurement: Visual Analogue Scale (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSahand Samieerad

Mashhad University of Medical Sciences

samieerads@mums.ac.ir+98 51 3882 9501

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026