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The comparison of treatment success rate of injection of hyaluronic acid versus PRP for patients with TMJ osteoarthritis.

The comparison of treatment success rate of arthroscopic arthrocentesis by injection of PRP versus hyaluronic acid (single or combinative) for patients with TMJ osteoarthritis.

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150613022697N6
Enrollment
30
Registered
2018-11-22
Start date
2018-10-12
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Temporomandibular joint osteoarthritis. Temporomandibular joint disorders

Interventions

Intervention 1: Intervention group: arthroscopic arthrocentesis with intra-articular injection of 1cc hyaluronic acid. Intervention 2: Intervention group: arthroscopic arthrocentesis with intra-articu

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 60 Years

Inclusion criteria

Inclusion criteria: All of the patients with TMJ osteoarthritis (in one or both Joints) with age range 15-60 years old who received conservative treatment. Patients with ASA 1 or 2 status Patients with normal cardiovascular or coagulation system

Exclusion criteria

Exclusion criteria: Patients with previous TMJ surgery Patients with the history of neurological, immunologic head & neck and TMJ malignancy Patients with the history of problem in connective tissue such as rheumatoid arthritis Patients with the history of NSAIDS usage. Patients with the allergy to HA and PRP

Design outcomes

Primary

MeasureTime frame
Maximum Mouth Opening (MMO) rate. Timepoint: One day before, 1, 3, 6 and 12 months after arthrocentesis. Method of measurement: Ruler in millimeters.;Jaw protrusive movement rate. Timepoint: One day before, 1, 3, 6 and 12 months after arthrocentesis. Method of measurement: Ruler in millimeters.;Jaw lateral Movement rate. Timepoint: One day before, 1, 3, 6 and 12 months after arthrocentesis. Method of measurement: Ruler in millimeters.;Joint sounds presence. Timepoint: One day before, 1, 3, 6 and 12 months after arthrocentesis. Method of measurement: Yes / No.;Joint pain amount. Timepoint: One day before, 1, 3, 6 and 12 months after arthrocentesis. Method of measurement: VAS scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSahand Samiee rad

Mashhad University of Medical Sciences

samieerads@mums.ac.ir+98 51 3882 9501

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026