Examining the topical effectiveness of Joint‘s cream on patients with Osteoarthritis of the knee.

Examining the topical effectiveness of Joint‘s cream (A production of Iranian Traditional Medicine - ITM) on pain and function in patients with Osteoarthritis of the knee.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150613022689N6

Enrollment

Registered

2018-03-19

Start date

2018-04-21

Completion date

Unknown

Last updated

2018-03-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of the knee. Osteoarthritis of knee

Interventions

Intervention 1: Control group: Patients in the control group perform the usual program of treatment for osteoarthritis (including patient education, exercise, weight loss, use insoles, physiotherapy,

Eligibility

Sex/Gender

All

Age

40 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 40 years Having diagnostic criteria for knee osteoarthritis (defined by the American College of Rheumatology) Having grade 2 or 3 osteoarthritis according to radiological criteria Having a BMI of 20-35

Exclusion criteria

Exclusion criteria: History of rheumatoid arthritis History of knee or hip replacement surgery in the affected joint History of any lower limb surgery over the past 6 months History of intra-articular corticosteroid injection in the last 6 months History of intra-articular injection of gel and PRP in the last year The onset of opioid analgesics or oral corticosteroids over the past four weeks

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: At the beginning of the study (before intervention), 4 and 8 weeks after the use of joint cream. Method of measurement: Using visual analog scale and KOOS questionnaires.;Function. Timepoint: At the beginning of the study (before intervention), 4 and 8 weeks after the use of joint cream. Method of measurement: Using visual analog scale and KOOS questionnaires.	—

Secondary

Measure	Time frame
Localized swelling. Timepoint: At the beginning of the study (before intervention), 4 and 8 weeks after the use of joint cream. Method of measurement: Using visual analog scale and KOOS questionnaires and 6MWT, Timed up and go test tests and 30 second chair stand test.;Range of knee joint movements. Timepoint: At the beginning of the study (before intervention), 4 and 8 weeks after the use of joint cream. Method of measurement: Using visual analog scale and KOOS questionnaires and 6MWT, Timed up and go test tests and 30 second chair stand test.;Life satisfaction. Timepoint: At the beginning of the study (before intervention), 4 and 8 weeks after the use of joint cream. Method of measurement: Using visual analog scale and KOOS questionnaires and 6MWT, Timed up and go test tests and 30 second chair stand test.	—

Measure

Time frame

Localized swelling. Timepoint: At the beginning of the study (before intervention), 4 and 8 weeks after the use of joint cream. Method of measurement: Using visual analog scale and KOOS questionnaires and 6MWT, Timed up and go test tests and 30 second chair stand test.;Range of knee joint movements. Timepoint: At the beginning of the study (before intervention), 4 and 8 weeks after the use of joint cream. Method of measurement: Using visual analog scale and KOOS questionnaires and 6MWT, Timed up and go test tests and 30 second chair stand test.;Life satisfaction. Timepoint: At the beginning of the study (before intervention), 4 and 8 weeks after the use of joint cream. Method of measurement: Using visual analog scale and KOOS questionnaires and 6MWT, Timed up and go test tests and 30 second chair stand test.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactEbrahim Khadem Azghadi

Tehran University of Medical Sciences

ekhadem@tums.ac.ir+98 21 6675 4167

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026