Comparison of the effect of chlorhexidine mouthwash and irsha mouthwash drop in the prevention of pulmonary infection in hospitalized patients in the intensive care unit

Comparison of the effect of chlorhexidine mouthwash with irsha mouthwash drop on probable ventilator-associated pneumonia in intensive care unit

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20150613022681N2

Enrollment

Registered

2020-04-30

Start date

2019-03-21

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator associated pneumonia. Ventilator associated pneumonia

Interventions

Intervention 1: Intervention group: washing of mouth and teeths with 10 cc chlorhexidine 0.2% three times of day until 5 days. Intervention 2: Intervention group: washing of mouth and teeths with 20-2

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years Requires mechanical ventilation for at least 48 hours Satisfaction to participate in the study Patients with natural teeth

Exclusion criteria

Exclusion criteria: Specify any damage caused by endotracheal intubation. Extubation before 5 days Patient death within 5 days of follow-up

Design outcomes

Primary

Measure	Time frame
Ventilator associated pneumonia incidence. Timepoint: After using the drug on a daily basis up to 5 days. Method of measurement: Clinical pulmonary infection score.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBabak Alikiai

Esfahan University of Medical Sciences

alikiaiib@med.mui.ac.ir+98 31 3620 2020

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026