Bacterial vaginosis. Acute vaginitis
Conditions
Interventions
Intervention 1: Intervention group: Patients will receive metronidazole tablet 500 mg twice daily for one week. Moreover, patients will receive a 50000 IU soft gel capsule of vitamin D per day for 5 d
Sponsors
Kerman University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
16 Years to 50 Years
Inclusion criteria
Inclusion criteria: Premenopausal women aged> 16 years Serum 25 (OH) D concentration of < 20 ng / ml Having bacterial vaginosis
Exclusion criteria
Exclusion criteria: Concurrent vaginal candidiasis or trichomoniasis Being in the bleeding phase of menstruation Systemic or vaginal use of antibiotics in the past 2 weeks Pregnancy Lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of patients respond clinically defined as those with normal vaginal discharge, vaginal secretion pH < 4.5, and negative whiff test. Timepoint: At baseline and 14 days after completion of treatment. Method of measurement: Self reported characteristics of vaginal discharge including odor and color of discharge, measurement of pH of vaginal secretion with pH strips, for performing the whiff test, several drops of 10% potassium hydroxide is added to the sample of vaginal discharge. Release of a fish amine odor indicates a positive whiff test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Percentage of clue cells on microscopic examination of the vaginal wet mount. Timepoint: At baseline and 14 days after completion of the study. Method of measurement: Microscopic examination of vaginal discharge.;Serum concentration of 25 (OH) vitamin D. Timepoint: At baseline and end of the study. Method of measurement: Laboratory tests in hospital laboratory. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNaemeh Nikvarz
Kerman University of Medical Sciences
Outcome results
None listed