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Evaluation of effects of calcipotriol ointment on healing of skin graft donor site

Evaluation of effects of calcipotriol ointment on healing of split thickness skin graft donor site: a single blind controlled trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20150609022637N5
Enrollment
48
Registered
2018-08-27
Start date
2018-06-22
Completion date
Unknown
Last updated
2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burn injury. Burn and corrosion, body region unspecified

Interventions

Intervention 1: Intervention group: Calcipotriol ointment 0.005% (Tehran Shimi Company) will be applied topically on the donor site every other day for 10 days. Intervention 2: Control group: No inter

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients undergo split thickness skin graft Patients sign informed consent form

Exclusion criteria

Exclusion criteria: Infection of the donor site Bleeding of the donor site Pregnancy Lactation Hypercalcemia Hyperphosphatemia Renal failure Hepatic impairment Sepsis

Design outcomes

Primary

MeasureTime frame
Percent of epithelialization of the donor site. Timepoint: 10 days after the intervention. Method of measurement: Calculation of the ratio of the surface area of the epithelialized parts to the total surface area of the donor site.

Secondary

MeasureTime frame
Number of episodes of the donor site infection. Timepoint: Before the intervention and 3, 6, 8 and 10 days after the intervention. Method of measurement: Inspection of the donor site and/or microbial culture of wound secretions.;Number of episodes of the donor site bleeding. Timepoint: Before the intervention and 3, 6, 8 and 10 days after the intervention. Method of measurement: Inspection of the donor site.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNaemeh Nikvarz

Kerman University of Medical Sciences

nnikvarz@kmu.ac.ir+98 34 3132 5017

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026