Lichen planus. Lichen planus
Conditions
Interventions
Intervention 1: Control Group : The Control group Patients receive mouthwash containing corticosteroid (0.5 mg of dexamethasone in 5 ml of water) as a standard first-line treatment
Then 30 minutes later, 100,000 units of nystatin solution is applied to prevent candidiasis. Treatment with mouthwash is done 4 times a day. In addition, patients are treated with sham photodynamic th
Then, after 15 minutes, the lesion and 0.5 mm around the lesion a re exposed to sham laser (placebo) In a way that the patient is unaware laser unit is off due to wearing protective eyewear. In order
Then, 30 minutes later, 100,000 units of nystatin solution is applied to prevent candidiasis. Treatment with mouthwash is done 4 times a day. In addition, patients in the intervention group are treate
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with ulcerative-erosive oral lichen planus, whose disease was confirmed by histopathological examination.
Exclusion criteria
Exclusion criteria: Lesions that have evidence of dysplasia in the histopathological view contact or medicinal lichenoid lesions patients who have received oral treatment for their lichen planus during the last month pregnant and lactating patients people with uncontrolled systemic disease photosensitive people
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain Score. Timepoint: Before starting intervention , one week, two weeks, one month and two months after starting intervention. Method of measurement: Visual Analogue Scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Lesion size score. Timepoint: Before starting intervention, one week, two weeks, one month and two months after starting intervention. Method of measurement: Graded abslang. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFaezeh Khozeimeh
Esfahan University of Medical Sciences
Outcome results
None listed