Diabetes mellitus. Non-insulin-dependent diabetes mellitus
Conditions
Interventions
Intervention 1: Sage leaf extract at the dose of one 500 mg capsule every 8 hours besides synthetic anti-hyperglycemic and anti-hyperlipidemic drugs are administered to a group of about 30 patients fo
Treatment - Drugs
Placebo
Sage leaf extract at the dose of one 500 mg capsule every 8 hours besides synthetic anti-hyperglycemic and anti-hyperlipidemic drugs are administered to a group of about 30 patients for 2 months.
One placebo capsule every 8 hours besides synthetic anti-hyperglycemic and anti-hyperlipidemic drugs are administered to a group of about 30 patients for 2 months.
Sponsors
Iranian Academic Center for Education, Culture and Research Institute of Medicinal Plants
Tehran University of Medical Sciences Diabetes Research Center
Eligibility
Sex/Gender
All
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Iranian male and female type 2 diabetic outpatients; patients aged 40 to 60 years; patients with blood HbA1c levels below 8%; patients with serum LDL levels from 100 mg/dl to 130 mg/dl; patients receiving standard therapy with synthetic anti-hyperglycemic and anti-hyperlipidemic drugs. Exclusion criteria: Patients receiving insulin; patients with cardiac, renal, hepatic, hematological diseases, hypothyroidism, tachycardia, vertigo and seizure; patients with a history of gallstones or gall bladder surgery; patients using estrogen, steroid, beta-blocker and thiazide; pregnant women; women planning pregnancy; breast-feeding women.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fasting serum glucose level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Glycosylated hemoglobin blood level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;LDL serum level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit). | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum triglyceride level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Serum total cholesterol level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Serum creatinine level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Serum 2 hour postprandial glucose level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Serum SGOT level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Serum SGPT level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Serum HDL level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Body mass index. Timepoint: 2 months. Method of measurement: Weighing scales and tape. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Saeed Kianbakht
Iranian Academic Center for Education, Culture and Research Institute of Medicinal Plants
Outcome results
None listed