Efficacy of epinephrine in combination with prednisolone compared with epinephrine alone in patients with cardiopulmonary arrest

Investigation the effect of epinephrine in combination with prednisolone on neurological complications in patients with cardiopulmonary arrest

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015060822623N1

Enrollment

Registered

2015-08-15

Start date

2015-06-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiopulmonary arrest. Pulmonary heart disease and diseases of pulmonary circulation

Interventions

Intervention 1: We administer epinephrine in combination with 40 mgr intravenous prednisolone for the first group of patients with cardiopulmonary arrest. Intervention 2: We administer just epinephri

Treatment - Drugs

We administer epinephrine in combination with 40 mgr intravenous prednisolone for the first group of patients with cardiopulmonary arrest

We administer just epinephrine in second group of patients.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: all patients with cardiopulmonary arrest that CPR done for them Exclusion criteria: patients that was died before receive to hospital; patient with just pulmonary arrest without heart arrest; in patient that infusion was not possible

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
CPR outcome. Timepoint: After the Cardiopulmonary recession. Method of measurement: Survive or expire.	—

Secondary

Measure	Time frame
Neurological complications. Timepoint: 24 hour and one week after CPR. Method of measurement: By CPC scure.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Esmat Seyedi

Mashhad University of Medical Sciences

seyedie921@mums.ac.ir+98 518525312

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026