Healing of Large Periapical Lesions Using Two Different Drugs

Evaluation of the Healing of Large Periapical Lesions Using Two Intracanal Medicaments, a Randomized Clinical Trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2015060822615N1

Enrollment

Registered

2016-06-26

Start date

2016-03-08

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic apical periodontitis. Apical or periapical granuloma Apical periodontitis NOS

Interventions

Intervention 1: Intervention group 1: Using calcium hydroxide cement as inter-session intra-canal drug. Intervention 2: intervention group 2: Using double antibiotic paste as inter-session intra-canal

Treatment - Drugs

Intervention group 1: Using calcium hydroxide cement as inter-session intra-canal drug.

intervention group 2: Using double antibiotic paste as inter-session intra-canal drug.

Eligibility

Sex/Gender

All

Age

15 Years to 30 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients having periapical lesions larger than 5mm in anterior region of maxilla; patients having 15-30 years of age; patients with necrotic teeth not treated endodonticaly previously; patients should be aware that they are part of a research and should sign the consent. Exclusion criteria: Patients with any systemic disease.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Diamater of periapical lesion. Timepoint: 6,12,18,24 months after interventions. Method of measurement: Standard radiography and ruller.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Majid Kazem

Dental School, Shahid Beheshti University of Medical Sciences

majidkazem@yahoo.com majidkazem@sbmu.ac.ir+98 21 2240 3010

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 6, 2026