Osteoarthritis. Primary arthrosis of other joints
Conditions
Interventions
Intervention 1: Saqez cream prepared by researcher, Knee local use, Dosage 2 grams per use, 3 times a day for 3 months. Intervention 2: Pluse control group: diclofenac gel 1 % ( Iran najo ) ,3 times
Treatment - Drugs
Saqez cream prepared by researcher, Knee local use, Dosage 2 grams per use, 3 times a day for 3 months
Pluse control group: diclofenac gel 1 % ( Iran najo ) ,3 times daily, 2 grams, for 3 months
Sponsors
Islamic Azad University, Pharmaceutical Sciences Branch
Eligibility
Sex/Gender
All
Age
35 Years to 85 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Patient's written consent; radiographic changes; primary knee osteoarthritis grade 2 and 3; age between 35 – 85; patients who did not receive topical treatment or received previous topical treatment for at least two weeks before they start on this trial. All patients must be stable on their current oral therapy. Exclusion criteria: Patients who needs more than 2 grams of acetaminophen in order to control pain; Those who need to use other oral or intravenous analgesics; Unwilling to continue or to participate in the study any further; Sensitivity to study drugs; Patients with other bone joint disorders: ( Rhumatoid Arthrities, Gout, Pseudo Gout, Infected Arthrities, Metabolic Arthrities, Traumatic Arthrities ) ; Infections and malignancy disease; Joint replacement; Fibro myalgia; Knee corticosteroid injection in the past 3 months, Pregnancy, oral and local use of corticosteroids; Pationts with active Renal, Liver and Peptic Ulcer Disease; Alcohol addicted; Drug Abuse
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Physical function. Timepoint: 2 Weeks,6 weeks and 12 weeks after baseline. Method of measurement: Womac questionaries.;Stiffness. Timepoint: 2 Weeks,6 weeks and 12 weeks after baseline. Method of measurement: Womac questionaries.;Pain. Timepoint: 2 Weeks,6 weeks and 12 weeks after baseline. Method of measurement: Womac questionaries. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mehdi Rajabi
Islamic Azad University, Pharmaceutical Sciences Branch
Outcome results
None listed